Scientific publications
2013
W. Den Otter, R.J.A. Van Moorselaar, J.J.L. Jacobs, R. Ter Haar, J.W. Koten, Z. Dobrowolski, W. Lipczynski, V. Pasukoniene, D. Characiejus, F. Jankevicius, R. Eidukevicius, T.M. De Reijke.
Role of Marker Lesion when Applying Intravesical Instillations of IL-2 for Non-muscle-invasive Bladder Cancer Comparison of the Therapeutic Effects in Two Pilot Studies
Anticancer Res May 33 : 2099-2105 (2013)
P.G.P.M. Ziekman, W. Den Otter, J.F.V. Tan, E. Teske, J. Kirpensteijn, J.W. Koten, J.J.L. Jacobs.
Intratumoural Interleukin-2 Therapy Can Induce Regression of Non-resectable Mastocytoma in Dogs.
Anticancer Research 33:161-165 (2013).
T.M. Van der Sluis, I.V. Bijnsdorp, J.J.L. Jacobs, E.J. Meuleman, L. Rozendaal, A.A. Geldof, R.J.A. van Moorselaar, A.N. Vis.
Serum testosterone plays an important role in the metastatic ability of castration resistant prostate cancer.
World J Urol. 31:261-6 (2013).
Role of Marker Lesion when Applying Intravesical Instillations of IL-2 for Non-muscle-invasive Bladder Cancer Comparison of the Therapeutic Effects in Two Pilot Studies
Anticancer Res May 33 : 2099-2105 (2013)
P.G.P.M. Ziekman, W. Den Otter, J.F.V. Tan, E. Teske, J. Kirpensteijn, J.W. Koten, J.J.L. Jacobs.
Intratumoural Interleukin-2 Therapy Can Induce Regression of Non-resectable Mastocytoma in Dogs.
Anticancer Research 33:161-165 (2013).
T.M. Van der Sluis, I.V. Bijnsdorp, J.J.L. Jacobs, E.J. Meuleman, L. Rozendaal, A.A. Geldof, R.J.A. van Moorselaar, A.N. Vis.
Serum testosterone plays an important role in the metastatic ability of castration resistant prostate cancer.
World J Urol. 31:261-6 (2013).
2012
P. Verhoef, J.W.W. Coeberg, J.J.L. Jacobs
Vijftig jaar Federa (1959-2009). Een beknopte geschiedenis en vooruitblik van de Federatie van Medisch Wetenschappelijke Verenigingen.
[Fifty years of Federa (1959-2012). A comprehensive history and future prospective of the Dutch Federation of Medical Scientific Societies]
Book. Erasmus Publishing / Federa, Rotterdam 2012. ISBN 978-90-5235-213-8
Vijftig jaar Federa (1959-2009). Een beknopte geschiedenis en vooruitblik van de Federatie van Medisch Wetenschappelijke Verenigingen.
[Fifty years of Federa (1959-2012). A comprehensive history and future prospective of the Dutch Federation of Medical Scientific Societies]
Book. Erasmus Publishing / Federa, Rotterdam 2012. ISBN 978-90-5235-213-8
2011
D. Characiejus, V. Pašukonienė, J.J.L. Jacobs, R. Eidukevičius, F. Jankevičius, N. Dobrovolskienė, M. Mauricas, R.J.A. Van Moorselaar, W. Den Otter.
Prognostic significance of peripheral blood CD8highCD57+ lymphocytes in bladder carcinoma patients after intravesical IL-2.
Anticancer Research 31:699-703(2011).
D. Characiejus, J.J.L. Jacobs, V. Pašukonienė, N. Kazlauskaitė, V. Danileviči, M. Mauricas, W. Den Otter.
Prediction of clinical response in cancer immunotherapy.
Anticancer Research 31:639-47 (2011).
J.J.L. Jacobs, D. Characiejus, R. Tomova, J. Baran, J. Bubenik, M. Zembala, Z. Krastev, R.J. Scheper, G. Pawelec, W. Den Otter.
Local, rather than systemic immunotherapy has therapeutic efficacy against metastasized cancer.
Trends in Cancer Research 7:1-14 (2011).
Prognostic significance of peripheral blood CD8highCD57+ lymphocytes in bladder carcinoma patients after intravesical IL-2.
Anticancer Research 31:699-703(2011).
D. Characiejus, J.J.L. Jacobs, V. Pašukonienė, N. Kazlauskaitė, V. Danileviči, M. Mauricas, W. Den Otter.
Prediction of clinical response in cancer immunotherapy.
Anticancer Research 31:639-47 (2011).
J.J.L. Jacobs, D. Characiejus, R. Tomova, J. Baran, J. Bubenik, M. Zembala, Z. Krastev, R.J. Scheper, G. Pawelec, W. Den Otter.
Local, rather than systemic immunotherapy has therapeutic efficacy against metastasized cancer.
Trends in Cancer Research 7:1-14 (2011).
2010
R. Tomova, K. Antonov, A. Ivanova, J.J.L. Jacobs, J.W. Koten, W. Den Otter, Z. Krastev.
Low-dose IL-2 therapy reduces HCV RNA and HBV DNA: case report.
Anticancer Research 29 : 5241-4 (2010).
D. Characiejus, J. Hodzic, J.J.L. Jacobs.
"First do no harm" and the importance of prediction in oncology.
EPMA Journal 1 : 369-75 (2010).
R.J.E. Stewart, J.J.L. Jacobs, J.W. Koten, W. Den Otter.
Local interleukin-2 therapy of bovine vulval papilloma and carcinoma complex.
Veterinary Record 167 : 825-6 (2010).
J.J.L. Jacobs, D. Characiejus, V. Pašukonienė, F. Jankevičius, R.J.A. Van Moorselaar, M. Mauricas W. Den Otter.
Recurrences of Superficial Bladder Carcinoma are Associated with a Raise of CD8highCD57+ and CD8low T Lymphocytes in Peripheral Blood.
The Open Cancer Immunology Journal 3 : 8-14 (2010).
Low-dose IL-2 therapy reduces HCV RNA and HBV DNA: case report.
Anticancer Research 29 : 5241-4 (2010).
D. Characiejus, J. Hodzic, J.J.L. Jacobs.
"First do no harm" and the importance of prediction in oncology.
EPMA Journal 1 : 369-75 (2010).
R.J.E. Stewart, J.J.L. Jacobs, J.W. Koten, W. Den Otter.
Local interleukin-2 therapy of bovine vulval papilloma and carcinoma complex.
Veterinary Record 167 : 825-6 (2010).
J.J.L. Jacobs, D. Characiejus, V. Pašukonienė, F. Jankevičius, R.J.A. Van Moorselaar, M. Mauricas W. Den Otter.
Recurrences of Superficial Bladder Carcinoma are Associated with a Raise of CD8highCD57+ and CD8low T Lymphocytes in Peripheral Blood.
The Open Cancer Immunology Journal 3 : 8-14 (2010).
2009
R. Tomova, K. Antonov, A. Ivanova, J.J.L. Jacobs, J.W. Koten, W. Den Otter, Z.Krastev
Low-dose IL-2 therapy reduces HCV RNA and HBV DNA: case report.
Anticancer Res. 29 : 5241-4 (2009).
J.J.L. Jacobs, D. Characiejus, R.J. Scheper, R.J. Stewart, J.F.V. Tan, R. Tomova, Z. Krastev, W.Den Otter.
The Amiens Strategy: Small Phase III Trials for Clinically Relevant Progress in the War Against Cancer.
Journal of Clinical Oncology 27 : 3062-3 (2009).
Low-dose IL-2 therapy reduces HCV RNA and HBV DNA: case report.
Anticancer Res. 29 : 5241-4 (2009).
J.J.L. Jacobs, D. Characiejus, R.J. Scheper, R.J. Stewart, J.F.V. Tan, R. Tomova, Z. Krastev, W.Den Otter.
The Amiens Strategy: Small Phase III Trials for Clinically Relevant Progress in the War Against Cancer.
Journal of Clinical Oncology 27 : 3062-3 (2009).
2008
W. Den Otter, J.J.L. Jacobs, J.J. Battermann, G.J. Hordijk, Z. Krastev, E.V. Moiseeva, R.J.E. Stewart, P.G.P.M. Ziekman, J.W. Koten.
Local therapy of cancer with free IL-2.
Cancer Immunology and Immunotherapy 57 : 931-950 (2008).
Local therapy of cancer with free IL-2.
Cancer Immunology and Immunotherapy 57 : 931-950 (2008).
2007
C. Hiemstra, Z. Zhong, S.R. Van Tomme, M.J. van Steenbergen, J.J.L. Jacobs, W. Den Otter, W.E. Hennink & J. Feijen.
In vitro and in vivo protein delivery from in situ forming poly(ethylene glycol)–poly(lactide) hydrogels.
Journal of Controlled Release 119 : 320-7 (2007).
R.J.E. Stewart, J.W. Koten, M. Hack, S. Hateboer, J.J.L. Jacobs, A. Masztalerz, W. Den Otter.
Histopathological studies on the effect of Local IL-2 therapy in Bovine Ocular Squamous Cell Carcinoma and Bovine Vulval Papilloma and Carcinoma Complex: mechanism of tumour rejection.
Chapter 5 in Rachel J. E. Stewart. Local IL-2 and IL-12 treatment of Bovine Ocular Squamous Cell Carcinoma (BOSCC) and Bovine Vulval Papilloma and Carcinoma Complex (BVPCC) in Cattle in Zimbabwe. Thesis, University Utrecht, 2007.
In vitro and in vivo protein delivery from in situ forming poly(ethylene glycol)–poly(lactide) hydrogels.
Journal of Controlled Release 119 : 320-7 (2007).
R.J.E. Stewart, J.W. Koten, M. Hack, S. Hateboer, J.J.L. Jacobs, A. Masztalerz, W. Den Otter.
Histopathological studies on the effect of Local IL-2 therapy in Bovine Ocular Squamous Cell Carcinoma and Bovine Vulval Papilloma and Carcinoma Complex: mechanism of tumour rejection.
Chapter 5 in Rachel J. E. Stewart. Local IL-2 and IL-12 treatment of Bovine Ocular Squamous Cell Carcinoma (BOSCC) and Bovine Vulval Papilloma and Carcinoma Complex (BVPCC) in Cattle in Zimbabwe. Thesis, University Utrecht, 2007.
2006
R.J.E. Stewart, F.W.G. Hill, A. Masztalerz, J.J.L. Jacobs, J.W. Koten & W. Den Otter.
Treatment of ocular squamous cell carcinomas in cattle using Interleukin 2.
Veterinary Record 159 : 668-672 (2006).
S. Kezic, F. Calkoen, M.A.M. Wenker, J.J.L. Jacobs & M.M. Verberk.
Genetic polymorphism of metabolic enzymes modifies the risk of chronic solvent-induced encephalopathy.
Toxicology and Industrial Health 22: 1-9 (2006).
R. Tomova, J. Pomakov, J.J.L. Jacobs, D. Adjarov, S. Popova, I. Altankova, W. Den Otter, & Z. Krastev.
Changes in cytokine profile during local IL-2 therapy in patients with different malignancies.
Anticancer Research 26 : 2037-47 (2006).
C.M. de Jongh, M.M. Verberk, C.E.T. Withagen, J.J.L. Jacobs, T. Rustemeyer &, S. Kezic.
Stratum corneum cytokines and skin irritation response to sodium lauryl sulphate.
Contact Dermatitis 54 : 325-33 (2006).
J.J.L.Jacobs*, C.L.Lehé*, H. Hasegawa, G.R. Elliott & P.K. Das. * contributed equally.
Skin irritants and contact sensitizers induce Langerhans cell migration and maturation at irritant concentration.
Experimental Dermatology 15 : 432–440 (2006).
C.L.Lehé*, J.J.L. Jacobs*, C.M.Hua, P. Courtellemont, G.R.Elliott & P.K. Das. * contributed equally.
Subtoxic concentrations of allergenic haptens induce LC migration and maturation in a human organotypic skin explant culture model: A novel method for identifying potential contact allergens.
Experimental Dermatology 15 : 421–431 (2006).
Treatment of ocular squamous cell carcinomas in cattle using Interleukin 2.
Veterinary Record 159 : 668-672 (2006).
S. Kezic, F. Calkoen, M.A.M. Wenker, J.J.L. Jacobs & M.M. Verberk.
Genetic polymorphism of metabolic enzymes modifies the risk of chronic solvent-induced encephalopathy.
Toxicology and Industrial Health 22: 1-9 (2006).
R. Tomova, J. Pomakov, J.J.L. Jacobs, D. Adjarov, S. Popova, I. Altankova, W. Den Otter, & Z. Krastev.
Changes in cytokine profile during local IL-2 therapy in patients with different malignancies.
Anticancer Research 26 : 2037-47 (2006).
C.M. de Jongh, M.M. Verberk, C.E.T. Withagen, J.J.L. Jacobs, T. Rustemeyer &, S. Kezic.
Stratum corneum cytokines and skin irritation response to sodium lauryl sulphate.
Contact Dermatitis 54 : 325-33 (2006).
J.J.L.Jacobs*, C.L.Lehé*, H. Hasegawa, G.R. Elliott & P.K. Das. * contributed equally.
Skin irritants and contact sensitizers induce Langerhans cell migration and maturation at irritant concentration.
Experimental Dermatology 15 : 432–440 (2006).
C.L.Lehé*, J.J.L. Jacobs*, C.M.Hua, P. Courtellemont, G.R.Elliott & P.K. Das. * contributed equally.
Subtoxic concentrations of allergenic haptens induce LC migration and maturation in a human organotypic skin explant culture model: A novel method for identifying potential contact allergens.
Experimental Dermatology 15 : 421–431 (2006).
2005 - Copromotor E.V. Moiseeva
2005 - Press and Nature Clinical Practice Oncology
Paper Jacobs, Hordijk et al. (2005)
A. King (2005).
IL-2 with radiotherapy: an effective treatment for late-stage nasopharyngeal carcinoma.
Nature Clinical Practice Oncology 2 (10): 486.
A. King (2005).
IL-2 with radiotherapy: an effective treatment for late-stage nasopharyngeal carcinoma.
Nature Clinical Practice Oncology 2 (10): 486.
2005
J.J.L. Jacobs, G.J. Hordijk, J.M Schulz, C.H.J. Terhaard, J.W. Koten, J.J. Battermann & W. Den Otter.
Treatment of stage III-IV nasopharyngeal carcinomas by external beam irradiation and local low doses of IL-2.
Cancer Immunology and Immunotherapy 54 : 647-654 (2005).
J.J.L. Jacobs, D. Sparendam & W. Den Otter.
Local interleukin 2 therapy is most effective against cancer when injected intratumourally.
Cancer Immunology and Immunotherapy 54 : 647-654 (2005).
Z. Krastev, V. Koltchakov, R. Tomova, S. Deredjian, A. Alexiev, D. Popov, B. Tomov, J.W. Koten, J. Jacobs & W. Den Otter.
Locoregional IL-2 low dose applications for gastrointestinal tumours.
World Journal of Gastroenterology 11 : 5525-5529 (2005)
E.V. Moiseeva, V.K. Bojenko, I.E. Sergeev, J.E. van Dijk, W. Den Otter & J.J.L. Jacobs.
Host factors determine early or late visible manifestation of mammary carcinoma.
Chapter 2 in E.V. Moiseeva, Original approaches to test anti-breast cancer drugs in a novel set of mouse models, Thesis, Utrecht, 2005.
E.V. Moiseeva, V.K. Bojenko, J.J.L. Jacobs & W. Den Otter.
Several haematological and serum biochemical parameters predict therapeutic effect of IL-2 against mouse mammary cancer.
Chapter 4 in E.V. Moiseeva, Original approaches to test anti-breast cancer drugs in a novel set of mouse models, Thesis, Utrecht, 2005.
E.V. Moiseeva, E.V. Svirshchewskaya, A.V. Chaadaeva, E.M. Rapoport, S.G. Semushina, I.V. Smirnova, W.G. Telford, J.J.L. Jacobs & W. Den Otter. Local interleukin-2 against breast cancer tested in spontaneous mouse models.
Chapter 5 in E.V. Moiseeva, Original approaches to test anti-breast cancer drugs in a novel set of mouse models, Thesis, Utrecht, 2005.
E.V. Moiseeva, A.V. Chaadaeva, S.G. Semushina, Yu.V. Demidova, J. Tan, J.J.L. Jacobs, J.E. van Dijk & W. Den Otter. Local interleukin-2 against breast cancer tested in spontaneous mouse models.
Chapter 8 in Ekatarina Moiseeva, Original approaches to test anti-breast cancer drugs in a novel set of mouse models, Thesis, Utrecht, 2005.
R.J.E. Stewart, A. Masztalerz, J.J.L. Jacobs & W. Den Otter.
Local Interleukin-2 and Interleukin-12 therapy of bovine ocular squamous cell carcinomas.
Veterinary Immunology and Immunopathology 106 : 277-284 (2005).
Treatment of stage III-IV nasopharyngeal carcinomas by external beam irradiation and local low doses of IL-2.
Cancer Immunology and Immunotherapy 54 : 647-654 (2005).
J.J.L. Jacobs, D. Sparendam & W. Den Otter.
Local interleukin 2 therapy is most effective against cancer when injected intratumourally.
Cancer Immunology and Immunotherapy 54 : 647-654 (2005).
Z. Krastev, V. Koltchakov, R. Tomova, S. Deredjian, A. Alexiev, D. Popov, B. Tomov, J.W. Koten, J. Jacobs & W. Den Otter.
Locoregional IL-2 low dose applications for gastrointestinal tumours.
World Journal of Gastroenterology 11 : 5525-5529 (2005)
E.V. Moiseeva, V.K. Bojenko, I.E. Sergeev, J.E. van Dijk, W. Den Otter & J.J.L. Jacobs.
Host factors determine early or late visible manifestation of mammary carcinoma.
Chapter 2 in E.V. Moiseeva, Original approaches to test anti-breast cancer drugs in a novel set of mouse models, Thesis, Utrecht, 2005.
E.V. Moiseeva, V.K. Bojenko, J.J.L. Jacobs & W. Den Otter.
Several haematological and serum biochemical parameters predict therapeutic effect of IL-2 against mouse mammary cancer.
Chapter 4 in E.V. Moiseeva, Original approaches to test anti-breast cancer drugs in a novel set of mouse models, Thesis, Utrecht, 2005.
E.V. Moiseeva, E.V. Svirshchewskaya, A.V. Chaadaeva, E.M. Rapoport, S.G. Semushina, I.V. Smirnova, W.G. Telford, J.J.L. Jacobs & W. Den Otter. Local interleukin-2 against breast cancer tested in spontaneous mouse models.
Chapter 5 in E.V. Moiseeva, Original approaches to test anti-breast cancer drugs in a novel set of mouse models, Thesis, Utrecht, 2005.
E.V. Moiseeva, A.V. Chaadaeva, S.G. Semushina, Yu.V. Demidova, J. Tan, J.J.L. Jacobs, J.E. van Dijk & W. Den Otter. Local interleukin-2 against breast cancer tested in spontaneous mouse models.
Chapter 8 in Ekatarina Moiseeva, Original approaches to test anti-breast cancer drugs in a novel set of mouse models, Thesis, Utrecht, 2005.
R.J.E. Stewart, A. Masztalerz, J.J.L. Jacobs & W. Den Otter.
Local Interleukin-2 and Interleukin-12 therapy of bovine ocular squamous cell carcinomas.
Veterinary Immunology and Immunopathology 106 : 277-284 (2005).
Best paper award
European Journal of Pharmaceutical Science (EJPS) best paper award 2005 for paper Bos, Jacobs et al. (2004)
2004
G.W. Bos, J.J.L. Jacobs, J.W. Koten , S. Van Tomme , T. Veldhuis , C.F. van Nostrum , W. den Otter & W.E. Hennink.
In situ crosslinked hydrogels loaded with interleukin-2 efficiently cure tumor-bearing mice.
European Journal of Pharmaceutical Sciences 21: 561-567 (2004)
J.J.L. Jacobs, C.L.Lehé, K.D.A. Cammans, P.K. Das & G.R. Elliott.
Assessment of contact allergens by dissociation of irritant and sensitizing properties.
Toxicology in Vitro 18 : 681-90 (2004).
In situ crosslinked hydrogels loaded with interleukin-2 efficiently cure tumor-bearing mice.
European Journal of Pharmaceutical Sciences 21: 561-567 (2004)
J.J.L. Jacobs, C.L.Lehé, K.D.A. Cammans, P.K. Das & G.R. Elliott.
Assessment of contact allergens by dissociation of irritant and sensitizing properties.
Toxicology in Vitro 18 : 681-90 (2004).
PhD Thesis (2003)
John J. L. Jacobs.
"Organotypic skin explant cultures to identify skin irritants and contact allergens".Thesis, University of Amsterdam. Email me @ JJLJacobs (at) yahoo.com
"Organotypic skin explant cultures to identify skin irritants and contact allergens".Thesis, University of Amsterdam. Email me @ JJLJacobs (at) yahoo.com
2003
C.L.Lehé*, J.J.L.Jacobs*, G.R.Elliott & P.K. Das. * contributed equally.
A two centre evaluation of the human organotypic skin explant culture model for screening contact allergens.
ATLA 31 : 553-561 (2003); correction 32 : 7 (2004).
T.J.P. Spoormakers, W.R. Klein, J.J.L. Jacobs, Th.S.G.A.M. Van Den Ingh, J.W. Koten & W. Den Otter.
Comparison of the efficacy of local treatment of Equine sarcoids with IL-2 or Cisplatin/IL-2.
Cancer Immunology and Immunotherapy 52 : 179-184 (2003).
A two centre evaluation of the human organotypic skin explant culture model for screening contact allergens.
ATLA 31 : 553-561 (2003); correction 32 : 7 (2004).
T.J.P. Spoormakers, W.R. Klein, J.J.L. Jacobs, Th.S.G.A.M. Van Den Ingh, J.W. Koten & W. Den Otter.
Comparison of the efficacy of local treatment of Equine sarcoids with IL-2 or Cisplatin/IL-2.
Cancer Immunology and Immunotherapy 52 : 179-184 (2003).
2002
J.J.L. Jacobs, C. Lehé, K.D.A. Cammans, P.K. Das & G.R. Elliott.
An in vitro model for detecting skin irritants: methyl green-pyronine staining of human skin explant cultures.
Toxicology in Vitro 16 : 581–588 (2002).
An in vitro model for detecting skin irritants: methyl green-pyronine staining of human skin explant cultures.
Toxicology in Vitro 16 : 581–588 (2002).
2001
J.J.L. Jacobs, C. Lehé, K.D.A. Cammans, K. Yoneda, P.K. Das & G.R. Elliott.
An automated method for quantification of immunostained human Langerhans cells.
Journal of Immunological Methods 247 : 73–82 (2001).
An automated method for quantification of immunostained human Langerhans cells.
Journal of Immunological Methods 247 : 73–82 (2001).
2000
J.J.L. Jacobs, C. Lehé, K.D.A. Cammans, P.K. Das & G.R. Elliott.
Methyl green-pyronine staining of porcine organotypic skin explant cultures: an alternative model for screening for skin irritants.
ATLA 28 : 279-92 (2000).
J.J.L. Jacobs, C. Lehé, K.D.A. Cammans, P.K. Das & G.R. Elliott. Screening of skin irritants by RNA detection as a viability marker in porcine organotypic skin explants. pp. 601-7 in Progress in the Reduction, Refinement and Replacement of Animal Experimentation (2000), Ed. by M. Balls, A.-M. van Zeller & M.E. Halder. Developments in Animal and Veterinary Sciences, volume 31. Elsevier Science B.V., Amsterdam, the Netherlands.
Methyl green-pyronine staining of porcine organotypic skin explant cultures: an alternative model for screening for skin irritants.
ATLA 28 : 279-92 (2000).
J.J.L. Jacobs, C. Lehé, K.D.A. Cammans, P.K. Das & G.R. Elliott. Screening of skin irritants by RNA detection as a viability marker in porcine organotypic skin explants. pp. 601-7 in Progress in the Reduction, Refinement and Replacement of Animal Experimentation (2000), Ed. by M. Balls, A.-M. van Zeller & M.E. Halder. Developments in Animal and Veterinary Sciences, volume 31. Elsevier Science B.V., Amsterdam, the Netherlands.
1999
J.J.L. Jacobs, E. Folkers & J. Vreeswijk.
Detection of Varicella Zoster virus and herpes simplex virus by polymerase chain reaction with degenerate primers.
Journal of Virological Methods 83 : 155–167 (1999).
E. Folkers, J.J.L. Jacobs, A.P. Oranje, F.J.W. ten Kate & J. Vreeswijk.
Immune response to Varicella-zoster virus infection in vivo immunoglobulins, complement and cellular infiltrates.
Chapter 5 in Elzo Folkers, Diagnostic aspects of human alphaherpes virus infections in de dermato-venereology, Thesis, University of Amsterdam, 1999.
Detection of Varicella Zoster virus and herpes simplex virus by polymerase chain reaction with degenerate primers.
Journal of Virological Methods 83 : 155–167 (1999).
E. Folkers, J.J.L. Jacobs, A.P. Oranje, F.J.W. ten Kate & J. Vreeswijk.
Immune response to Varicella-zoster virus infection in vivo immunoglobulins, complement and cellular infiltrates.
Chapter 5 in Elzo Folkers, Diagnostic aspects of human alphaherpes virus infections in de dermato-venereology, Thesis, University of Amsterdam, 1999.
1998
L.A. Everse, M.R Bernsen, L.H. Esquivel-Ccala, J.J.L. Jacobs, H.F.J. Dullens & W. Den Otter.
Effective cancer immunotherapy with immunization and low-dose IL-2 does not correlate with numerical changes in tumor-infiltrating leucocytes. Chapter 4 in Linda A. Everse, Preclinical indication in support of combined-modality treatment of cancer using radiotherapy and interleukin-2. Thesis, University Utrecht, 1998.
J.J.L. Jacobs.
Falsification of repression hypothesis. EL4 to Harrison G Pope Jr, Recovered memories of childhood sexual abuse.
British Medical Journal 316:488 – 489 #(1998).
Effective cancer immunotherapy with immunization and low-dose IL-2 does not correlate with numerical changes in tumor-infiltrating leucocytes. Chapter 4 in Linda A. Everse, Preclinical indication in support of combined-modality treatment of cancer using radiotherapy and interleukin-2. Thesis, University Utrecht, 1998.
J.J.L. Jacobs.
Falsification of repression hypothesis. EL4 to Harrison G Pope Jr, Recovered memories of childhood sexual abuse.
British Medical Journal 316:488 – 489 #(1998).
Contact me on science using [email protected]
Popular science
For my popular scientific publications I would like to refer to my Dutch site
